Last week my 81-year-old mother was diagnosed with myelodysplastic anemia, a rare bone marrow cancer often caused by exposure to Benzene, a solvent used in paint, cleaning products, gasoline and a myriad of household chemicals. My mother, however, had not been exposed to Benzene nor had ever taken chemotherapy drugs, another cause of the disease.
Myelodysplastic syndromes (MDS) are a group of diseases that affect the bone marrow and blood. Some types of MDS are mild and easily managed, while other types are severe and life-threatening. Mild MDS can grow more severe over time. It can also develop into a fast-growing, severe leukemia called acute myelogenous or myeloid leukemia. In MDS, the bone marrow does not make enough normal blood cells for the body. One, two or all three types of blood cells — red blood cells, white blood cells and platelets — may be affected. The marrow may also make immature cells called blasts. Blasts normally develop into red blood cells, white blood cells or platelets. In MDS, the blasts are abnormal and do not develop or function normally.
You first learn you have the disease when a simple blood test reveals you have a low blood count. Doctors may first try to determine if you have internal bleeding. To be diagnosed you must have a bone marrow biopsy done. Men more often have the disease than women. Usually patients are over 60. However, anyone of any age can have MDS, even children.
My mother’s red blood count cell is down to 4; her white blood cells and platelets are also very low. A week ago she started vomiting and could not stop, and was rushed to the hospital when she passed out. Over the last couple of months she hasn’t been eating much and has lost 15 pounds. She has been weak and sleeps a great deal. Some of you will recognize this as the body shutting down as it prepares for death. Her MDS is severe and she has been given only a few weeks to live.
Back in 2005 my mother had had 2 stents put in her heart. Afterwards, she was prescribed Plavix. Her doctor kept her on it for over 5 years. Last year when she changed doctors, she was taken off the drug immediately. Since then I have learned Plavix is supposed to be taken for only 6 months after having heart surgery. Apparently, the maker of Plavix, Bristol-Myers Squibb in conjunction with sanofi-aventis Pharmaceuticals, has not informed doctors strongly enough of this fact. While it would be hard to prove, the Internet is full of stories similar to my mother’s, of long-term use of Plavix causing MDS or AML, acute myeloid leukemia. Patients die within weeks of diagnosis. One day the patient is fine, living life normally, and the next is very ill, rushed to the hospital and then dies within a few weeks after being diagnosed.
Some 12,000 to 15,000 are diagnosed with MDS each year. Just how many are a result of taking Plavix is undetermined. However, if you look at the list of the severe side effects of this drug, you will find “Low Blood Counts due to Bone Marrow Failure” about 2/3 of the way down under “Rare side effects of Plavix Oral”.
While a small percentage of people suffer from this side effect, less than 1% of patients on this drug have a severe reaction, it is good to be aware it can happen to you or someone you love. Be sure your doctor closely monitors you while you are on the drug. Ask him if he is aware of this possible side effect, especially after long-term use. If you have been taking it for more than six months, ask your doctor why and get off of it ASAP. Don’t stop taking it on your own, but see your physician soon.
The best thing you can do for yourself is to look into more natural means of treating your heart disease. Don’t stop taking your drugs. But be your own advocate and look into alternatives–lose weight, exercise, eat legumes and garlic, take natural dietary supplements, put cinnamon on your cereal, change your diet–then go see your physician again to see if you are healthy enough to reduce or eliminate your drug treatment. Ask your doctor or pharmacist about any new drugs prescribed for you. What are the side effects? It may save your life!
Added note: My uncle was also a victim of long-term Plavix use. He had been taking it for several years. He developed an ulcer in his stomach from which he bled to death before it was detected.
Here is the list of rare side effects of Plavix from the Web.MD site:
| Retinal Hemorrhage | Severe |
| Hemorrhage from the Conjunctiva of the Eye | Severe |
| Pancreatitis | Severe |
| Eye Hemorrhage | Severe |
| Bleeding in the Abdomen | Severe |
| Hemorrhage Within the Skull | Severe |
| Vasculitis | Severe |
| Thrombotic Thrombocytopenic Purpura | Severe |
| Abnormally Low Blood Pressure | Severe |
| Interstitial Pneumonitis | Severe |
| Bronchospasm | Severe |
| Painful, Red or Swollen Mouth | Severe |
| Stomach Ulcer | Severe |
| Ulcer of the Duodenum | Severe |
| Inflammation of the Large Intestine | Severe |
| Acute Liver Failure | Severe |
| Hepatitis | Severe |
| Kidney Disease | Severe |
| Bloody Urine | Severe |
| Inflammation of the Skin with Blisters | Severe |
| Erythema Multiforme | Severe |
| Toxic Epidermal Necrolysis | Severe |
| Stevens-Johnson Syndrome | Severe |
| Hallucination | Severe |
| Bleeding from the Respiratory Tract | Severe |
| Throwing Up | Severe |
| Abnormal Liver Function Tests | Severe |
| Bleeding from Wound | Severe |
| Life Threatening Allergic Reaction | Severe |
| Giant Hives | Severe |
| Allergic Reaction caused by a Drug | Severe |
| Allergic Reaction causing Serum Sickness | Severe |
| Acquired Decrease of All Cells in the Blood | Severe |
| Low Blood Counts due to Bone Marrow Failure | Severe |
| Decreased Blood Platelets | Severe |
| Deficiency of Granulocytes a Type of White Blood Cell | Severe |
| Confused | Severe |
| Skin Disease Characterized by Swollen Itching Lesions | Less Severe |
| Arthritis | Less Severe |
| Muscle Pain | Less Severe |
| Fever | Less Severe |
| Taste Problems | Less Severe |
| Diarrhea | Less Severe |
| Bruise | Less Severe |
| Collection of Clotted Blood in an Organ, Space or Tissue | Less Severe |
If you are taking Plavix and are experiencing any of these side effects, please see your doctor ASAP. You should have a regular blood work-up at least every six months. Be sure to get a copy of your report. You can go online to compare your numbers to what is normal. If you see anything that concerns you, talk to your doctor and request further testing. e.g. If you are showing signs of anemia, be sure your doctor investigates further. Speak up for yourself; don’t let the doctor brush you off. Print out the list of side effects and take it with you to your doctor. Better to make a mistake and be fine than to ignore potential life-threatening symptoms.
http://www.mayoclinic.com/health/myelodysplastic-syndromes/DS00596
http://www.webmd.com/cancer/myelodysplastic-syndromes
http://www.uptodate.com/contents/patient-information-myelodysplastic-syndromes-mds-in-adults
October 25, 2011, Update: Today my mother passed away, only 2 1/2 weeks after being diagnosed.
Please, please be aware of the serious side-effects of prescription drugs. Do everything within your power to get off them by living a healthy lifestyle. Take control of your health. Don’t rely totally on drugs for your health issues.
















Nutrient based, pH balanced, clinically proven and hypoalergenic. It is formulated without parabens, sodium lauryl sulfate or sodium laureth sulfate, propylene glycol, animal products or by products, mineral oils or petroleum, FD&C or D&C dyes, or Phthalates. The first time you use it your skin feels so silky and hydrated. After 28 days there is a 665% increase in skin firmness, a 421% reduction in the appearance of wrinkles and 88% reduction in the appearance of fine lines. It’s a three step process morning and night that takes only 3 minutes. And it is guaranteed to work or your money back! Guaranteed. Click the Enfuselle photo for more information.


